SCHEMBL9170673

SCHEMBL9170673

CC(=O)Nc1ccc2[nH]nnc2c1O.[Ag]

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 10/20 0.45
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.38
ROCK2 O75116 1/20 0.36
ROCK1 Q13464 1/20 0.36
HPGD P15428 1/20 0.34
MEN1 O00255 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6051969 0.98 TOP2A (0.46) TOP2ANPC1POLBMAPTRAB9A
SCHEMBL9174819 0.82 KDM4E (0.37) TOP2ANPC1POLBMAPTRAB9A
SCHEMBL6052061 0.81 KDM4E (0.38) TOP2ANPC1POLBMAPTRAB9A
SCHEMBL9167989 0.80 ALDH1A1 (0.35) TOP2ANPC1POLBMAPTRAB9A
Silver SCHEMBL9174826 0.78 ALDH1A1 (0.36) TOP2ANPC1POLBMAPTRAB9A
SCHEMBL6052152 0.78 ALDH1A1 (0.36) TOP2ANPC1POLBMAPTRAB9A
SCHEMBL31388185 0.78 ALDH1A1 (0.46) POLBALDH1A1TSHRHPGDMEN1
SCHEMBL31388206 0.77 ALDH1A1 (0.44) POLBALDH1A1TSHRHPGDMEN1
Silver SCHEMBL9167993 0.76 CA1 (0.36) NPC1ALDH1A1TSHRROCK2ROCK1
SCHEMBL9163793 0.72 KDM4E (0.36) NPC1MAPTRAB9AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0144087-B2 Heat-developable color light-sensitive material KONISHIROKU PHOTO IND (JP) 1995-05-24 EP disclosed
EP-0174135-B2 HEAT-DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1992-06-17 EP disclosed
EP-0144087-B1 HEAT-DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-04-18 EP disclosed
EP-0136142-B1 THERMALLY DEVELOPABLE, LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-04-11 EP disclosed
US-4840882-A CONTAINING A VINYL SULFONYL HARDENER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-06-20 US disclosed
EP-0174135-B1 HEAT-DEVELOPABLE COLOR LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1989-04-26 EP disclosed
US-4770981-A MULTILAYER, DIFFUSION TRANSFER MATERIAL HAVING SPECIFIC BINDER CONCENTRATION; ANTIFOGGING AGENTS; COLOR SEPARATION; PHOTOTHERMOGRAPHY; DRY TREATMENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-09-13 US disclosed
US-4584267-A SILVER HALIDE, SILVER SALT, REDUCING AGENT, AND BINDER OF GELATIN OR DERIVATIVE AND POLYVINYL ALCOHOL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-22 US disclosed
EP-0174135-A2 Heat-developable color light-sensitive material KONICA CORPORATION (JP) 1986-03-12 EP disclosed
EP-0157639-A2 Heat-developable multilayered color photo-sensitive material KONICA CORPORATION (JP) 1985-10-09 EP disclosed
US-4543309-A BENZOTRIAZOLE SILVER SALT, REDUCING AGENT, BINDER, AMINO-MERCAPTO TRIAZOLE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-24 US disclosed
EP-0144087-A2 Heat-developable color light-sensitive material KONICA CORPORATION (JP) 1985-06-12 EP disclosed
EP-0136142-A2 Thermally developable, light-sensitive material KONICA CORPORATION (JP) 1985-04-03 EP disclosed