Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 12/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137712 | 0.84 | CACNA1H (0.36) | CACNA1HCACNA1CCACNA1BCACNA1GKDM4E | |
| SCHEMBL11716667 | 0.76 | CACNA1H (0.40) | CACNA1HCACNA1CCACNA1BXDHCACNA1G | |
| SCHEMBL12020771 | 0.76 | MAPT (0.42) | CACNA1HCACNA1CCACNA1BCACNA1GKDM4E | |
| SCHEMBL8872748 | 0.76 | CACNA1H (0.39) | CACNA1HCACNA1CCACNA1BDGAT1KCNH2 | |
| SCHEMBL9172104 | 0.75 | CACNA1H (0.56) | CACNA1HCACNA1CCACNA1BCACNA1G | |
| SCHEMBL10284436 | 0.73 | CACNA1H (0.40) | CACNA1HCACNA1CCACNA1BCACNA1GKDM4E | |
| SCHEMBL10959414 | 0.73 | PSMB8 (0.47) | PSMB8DGAT1SOAT1KCNH2KDM4E | |
| SCHEMBL12495908 | 0.72 | CACNA1H (0.42) | CACNA1HCACNA1CCACNA1BCACNA1G | |
| SCHEMBL15843980 | 0.72 | CACNA1H (0.56) | CACNA1HCACNA1CCACNA1BCACNA1G | |
| SCHEMBL18659788 | 0.72 | SCN10A (0.38) | CACNA1HCACNA1CCACNA1BCACNA1GKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650479-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994001411-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1994-01-20 | — | — | WO | disclosed |