Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 15/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 7/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.56 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391888 | 0.83 | RIPK1 (0.53) | CACNA1HCACNA1CCACNA1BCACNA1GEGLN1 | |
| SCHEMBL20623233 | 0.77 | CACNA1H (0.62) | CACNA1HCACNA1CCACNA1BCACNA1GEGLN1 | |
| SCHEMBL30822920 | 0.76 | CACNA1H (0.60) | CACNA1HCACNA1CCACNA1BCACNA1GEGLN1 | |
| SCHEMBL8872735 | 0.76 | CACNA1H (0.60) | CACNA1HCACNA1CCACNA1BCACNA1GEGLN1 | |
| SCHEMBL11716675 | 0.76 | CACNA1H (0.61) | CACNA1HCACNA1CCACNA1BCACNA1GEGLN1 | |
| SCHEMBL2418541 | 0.76 | CACNA1H (0.60) | CACNA1HCACNA1CCACNA1BCACNA1GEGLN1 | |
| SCHEMBL8264508 | 0.76 | CACNA1H (0.60) | CACNA1HCACNA1CCACNA1BCACNA1GEGLN1 | |
| SCHEMBL30822917 | 0.76 | CACNA1H (0.60) | CACNA1HCACNA1CCACNA1BCACNA1GEGLN1 | |
| SCHEMBL9172108 | 0.75 | PSMB8 (0.36) | CACNA1HCACNA1CCACNA1BCACNA1G | |
| SCHEMBL30822907 | 0.74 | CACNA1H (0.55) | CACNA1HCACNA1CCACNA1BCACNA1GEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650479-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994001411-A1 | BENZIMIDAZOLE DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1994-01-20 | — | — | WO | disclosed |