Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175017 | 0.88 | PTGER1 (0.61) | PTGER1MEN1ALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9165687 | 0.87 | PTGER1 (0.60) | PTGER1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9176184 | 0.87 | PTGER1 (0.57) | PTGER1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9176201 | 0.86 | PTGER1 (0.56) | PTGER1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9175688 | 0.86 | PTGER1 (0.56) | PTGER1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9176191 | 0.86 | PTGER1 (0.56) | PTGER1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9172696 | 0.84 | MEN1 (0.65) | PTGER1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9172445 | 0.83 | PTGER1 (0.59) | PTGER1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9162333 | 0.83 | PTGER1 (0.71) | PTGER1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9174411 | 0.82 | MEN1 (0.60) | PTGER1MEN1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420270-A | ANALGESICS; FOR TREATMENT OF PROSTAGLANDIN E2 MEDIATED DISEASES | G. D. SEARLE & CO. (US) | 1995-05-30 | — | — | US | claimed |
| US-5420270-A | ANALGESICS; FOR TREATMENT OF PROSTAGLANDIN E2 MEDIATED DISEASES | G. D. SEARLE & CO. (US) | 1995-05-30 | — | — | US | disclosed |