Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9165687 | 0.99 | PTGER1 (0.60) | PTGER1CYP3A4MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9172445 | 0.93 | PTGER1 (0.59) | PTGER1CYP3A4MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9169823 | 0.91 | PTGER1 (0.52) | PTGER1CYP3A4MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9171437 | 0.89 | PTGER1 (0.61) | PTGER1CYP3A4MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9172432 | 0.88 | PTGER1 (0.68) | PTGER1CYP3A4MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9175636 | 0.88 | PTGER1 (0.54) | PTGER1CYP3A4MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9169807 | 0.87 | PTGER1 (0.58) | PTGER1CYP3A4MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9173418 | 0.87 | PTGER1 (0.58) | PTGER1CYP3A4MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9171092 | 0.87 | PTGER1 (0.58) | PTGER1CYP3A4MEN1ALDH1A1CYP1A2 | |
| SCHEMBL8887008 | 0.87 | PTGER1 (0.72) | PTGER1CYP3A4MEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420270-A | ANALGESICS; FOR TREATMENT OF PROSTAGLANDIN E2 MEDIATED DISEASES | G. D. SEARLE & CO. (US) | 1995-05-30 | — | — | US | claimed |