SCHEMBL91742

SCHEMBL91742

Cc1cc(C)c(C(F)(F)Oc2cc(F)c(-c3ccc4c(F)c(C)c(F)cc4c3)c(F)c2)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91723 0.89 FFAR4 (0.32) ESR1ESR2
SCHEMBL91731 0.86
SCHEMBL91722 0.84
SCHEMBL91728 0.81
SCHEMBL91732 0.79 ESR1 (0.35) ESR1ESR2
SCHEMBL91766 0.79
SCHEMBL91739 0.79 FFAR4 (0.31)
SCHEMBL91719 0.77 CYP1A2 (0.33) ESR1ESR2
SCHEMBL91743 0.76 FFAR4 (0.31)
SCHEMBL14075290 0.76 ESR1 (0.38) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129002-B2 Compounds for use in liquid crystal media MERCK PATENT GMBH (DE) 2012-03-06 US disclosed