Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91723 | 0.89 | FFAR4 (0.32) | FFAR4 | |
| SCHEMBL91756 | 0.88 | AR (0.33) | FFAR4CYP11B1CYP11B2NT5E | |
| SCHEMBL91839 | 0.84 | FFAR4 (0.33) | FFAR4NT5E | |
| SCHEMBL91715 | 0.82 | SLC6A2 (0.32) | — | |
| SCHEMBL91753 | 0.82 | — | — | |
| SCHEMBL91711 | 0.81 | HSD17B1 (0.36) | FFAR4CYP11B1CYP11B2 | |
| SCHEMBL91743 | 0.81 | FFAR4 (0.31) | FFAR4 | |
| SCHEMBL91831 | 0.80 | MAPT (0.36) | — | |
| SCHEMBL91742 | 0.79 | ESR1 (0.31) | — | |
| SCHEMBL91722 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |