⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174940 | 1.00 | — | — | |
| SCHEMBL10661961 | 0.76 | — | — | |
| SCHEMBL11151628 | 0.71 | TDP1 (0.49) | — | |
| SCHEMBL17950438 | 0.71 | — | — | |
| SCHEMBL5717201 | 0.71 | TDP1 (0.58) | — | |
| SCHEMBL5756242 | 0.71 | — | — | |
| SCHEMBL5717198 | 0.71 | TDP1 (0.58) | — | |
| SCHEMBL5717407 | 0.71 | — | — | |
| SCHEMBL5759604 | 0.70 | ALDH1A1 (0.44) | — | |
| SCHEMBL5759608 | 0.70 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1037842-C | Substituted thiazolidine derivatives, pharmaceutical compositions and uses thereof | OTSUKA PHARMA CO LTD (JP) | 1998-03-25 | — | — | CN | disclosed |
| CN-1034864-C | Maillard reaction inhibitor | OTSUKA PHARMA CO LTD (JP) | 1997-05-14 | — | — | CN | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| CN-1069728-A | Maillard reaction inhibitor | OTSUKA PHARMA CO LTD (JP) | 1993-03-10 | — | — | CN | disclosed |