Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91751 | 0.87 | KMT2A (0.35) | KMT2AGBA1MAPTMEN1TDP1 | |
| SCHEMBL91754 | 0.87 | MAPT (0.34) | KMT2AGBA1MAPTMEN1GAA | |
| SCHEMBL91760 | 0.84 | KMT2A (0.34) | KMT2AGBA1MAPTMEN1TDP1 | |
| SCHEMBL91794 | 0.81 | KDM4E (0.31) | KMT2AMAPTGAAALDH1A1KDM4E | |
| SCHEMBL91736 | 0.81 | MAPT (0.39) | KMT2AMAPTMEN1TDP1ALDH1A1 | |
| SCHEMBL91718 | 0.79 | ESR1 (0.37) | ESR1CYP1A2 | |
| SCHEMBL91725 | 0.79 | NR1H4 (0.35) | KMT2AGBA1MAPTMEN1TDP1 | |
| SCHEMBL91814 | 0.79 | CYP1A2 (0.33) | KMT2AMAPTGAACYP1A2CYP2C19 | |
| SCHEMBL91719 | 0.79 | CYP1A2 (0.33) | KMT2AMAPTMEN1ALDH1A1ESR1 | |
| SCHEMBL91716 | 0.78 | MAPT (0.34) | KMT2AGBA1MAPTMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7419706-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-02 | — | — | US | disclosed |