Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91754 | 0.87 | MAPT (0.34) | MAPTCYP1A2CYP2C19ALDH1A1TP53 | |
| SCHEMBL91719 | 0.83 | CYP1A2 (0.33) | MAPTCYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL91736 | 0.83 | MAPT (0.39) | MAPTCYP1A2CYP2C19ALDH1A1TP53 | |
| SCHEMBL91705 | 0.82 | MAPT (0.41) | MAPTCYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL91814 | 0.79 | CYP1A2 (0.33) | MAPTCYP1A2CYP2C19KMT2AGAA | |
| SCHEMBL91745 | 0.78 | KMT2A (0.37) | MAPTCYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL91706 | 0.77 | ERN1 (0.32) | ESR1ESR2 | |
| SCHEMBL91722 | 0.76 | — | — | |
| SCHEMBL91717 | 0.76 | ERN1 (0.43) | MAPTCYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL91740 | 0.75 | MAPT (0.36) | MAPTCYP1A2CYP2C19ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7419706-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-02 | — | — | US | disclosed |