Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513558 | 0.87 | HTT (0.73) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL30669343 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL28377462 | 0.81 | HTT (0.54) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL11644757 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL9168557 | 0.79 | HTT (0.42) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL30982970 | 0.79 | HTT (0.51) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL30982613 | 0.79 | HTT (0.51) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL30982389 | 0.79 | HTT (0.51) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL20382944 | 0.79 | HTT (0.71) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL15613416 | 0.78 | HTT (0.46) | SMN1; SMN2HTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438053-A | Antibacterial agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| EP-0579221-A1 | Cephem compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |