Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.53 |
| ▸ | SENP2 | Q9HC62 | 8/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 7/20 | 0.52 |
| ▸ | SENP3 | Q9H4L4 | 6/20 | 0.52 |
| ▸ | SUMO2 | P61956 | 5/20 | 0.52 |
| ▸ | SUMO1 | P63165 | 5/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814617 | 1.00 | TP53 (0.56) | TP53CYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL9628366 | 0.86 | SENP2 (0.52) | TP53CYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL8746224 | 0.86 | RPS6KA3 (0.54) | CYP3A4TSHRPHLPP2SENP2SENP1 | |
| SCHEMBL9178619 | 0.86 | RPS6KA3 (0.54) | CYP3A4TSHRPHLPP2SENP2SENP1 | |
| SCHEMBL31539232 | 0.85 | SENP2 (0.48) | TP53PHLPP2SENP2SENP1SENP3 | |
| SCHEMBL15386662 | 0.85 | SENP2 (0.48) | TP53PHLPP2SENP2SENP1SENP3 | |
| SCHEMBL28677290 | 0.83 | SENP2 (0.61) | TP53CYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL29404827 | 0.83 | SENP2 (0.61) | TP53CYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL28367923 | 0.83 | SENP2 (0.61) | TP53CYP3A4TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL15386712 | 0.82 | SENP2 (0.58) | TP53CYP3A4TSHRMAPK1PHLPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424403-A | Preparation of aminoazo dyes | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| US-3979378-A | Water-soluble azo dyes having a substituted 2-hydroxypyridone (6) coupling component | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-09-07 | — | — | US | disclosed |