SCHEMBL9175229

SCHEMBL9175229

CCCCCc1ccccc1Br

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.55
TAAR1 Q96RJ0 3/20 0.54
NR1H2 P55055 1/20 0.45
NR1H3 Q13133 1/20 0.45
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
TSHR P16473 1/20 0.44
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
TLR8 Q9NR97 1/20 0.42
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
EP300 Q09472 1/20 0.42
KAT2A Q92830 1/20 0.42
KAT2B Q92831 1/20 0.42
KAT5 Q92993 1/20 0.42
SAE1 Q9UBE0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27574851 0.98 LIPG (0.58) LIPGTAAR1NR1H2NR1H3ALOX5
Phosphine SCHEMBL28275935 0.98 LIPG (0.53) LIPGTAAR1NR1H2NR1H3ALOX5
SCHEMBL6153468 0.98 LIPG (0.58) LIPGTAAR1NR1H2NR1H3ALOX5
SCHEMBL9835429 0.98 LIPG (0.58) LIPGTAAR1NR1H2NR1H3ALOX5
SCHEMBL14636127 0.98 LIPG (0.58) LIPGTAAR1NR1H2NR1H3ALOX5
SCHEMBL31591893 0.98 LIPG (0.58) LIPGTAAR1NR1H2NR1H3ALOX5
SCHEMBL31591865 0.98 LIPG (0.58) LIPGTAAR1NR1H2NR1H3ALOX5
SCHEMBL8766460 0.98 LIPG (0.58) LIPGTAAR1NR1H2NR1H3ALOX5
SCHEMBL28299135 0.98 LIPG (0.58) LIPGTAAR1NR1H2NR1H3ALOX5
SCHEMBL5599119 0.98 LIPG (0.58) LIPGTAAR1NR1H2NR1H3ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013102935-A2 Cu-MEDIATED ANNULATION FOR THE EFFECTIVE SYNTHESIS OF 3-SUBSTITUTED PHTHALIDES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-07-11 WO claimed
CN-117466938-A Luminescent material, ink composition and display panel 广州华星光电半导体显示技术有限公司 2024-01-30 CN disclosed
EP-4208465-A1 MEDIUM- OR MACRO-CYCLIC BENZYL-SUBSTITUTED HETEROCYCLE DERIVATIVES AND THEIR USES AS OREXIN-2 RECEPTOR AGONISTS Orexia Therapeutics Limited (GB) 2023-07-12 EP disclosed
WO-2022266193-A1 BICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2022-12-22 WO disclosed
CN-108191711-B Mixed liquid crystal for light-regulating and controlling giant electrothermal effect and preparation method thereof 西京学院 2020-08-18 CN disclosed
CN-110627831-A Bibiaryl acetal phosphines, their preparation and use in coupling reactions 东莞市均成高新材料有限公司 2019-12-31 CN disclosed
CN-106398080-B A kind of ammonium cross-linking type block copolymer/graphene composite material and preparation method thereof 北京化工大学 2018-12-04 CN disclosed
WO-2015063798-A1 A PROCESS FOR THE SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-05-07 WO disclosed
CN-103665347-A Organic semiconductor material containing alkylene fluorene and diketopyrrolopyrrole and preparation method and application thereof ZHOU MINGJIE 2014-03-26 CN disclosed
CN-1266098-C Substituted dicyclohexylalkyl diphenyl derivative with good low-tomp, mutual solubility, its preparation and application SHIJIAZHUANG YONGSHENG HUATSIN (CN) 2006-07-26 CN disclosed
CN-1477089-A Substituted dicyclohexylalkyl diphenyl derivative with good low-tomp, mutual solubility, its preparation and application 石家庄实力克液晶材料有限公司 2004-02-25 CN disclosed
US-5422360-A Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-06-06 US disclosed
CN-1024797-C Indole derivatives OTSUKA CHEMICAL CO LTD (JP) 1994-06-01 CN disclosed
EP-0531812-A1 Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-03-17 EP disclosed
CN-1049155-A INDOLE DERIVATIVES OTSUKA CHEMICAL CO LTD (JP) 1991-02-13 CN disclosed