Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367535 | 0.90 | PDE4A (0.53) | ALDH1A1ADORA3KAT2BPDE4APDE4B | |
| SCHEMBL9165034 | 0.88 | NPSR1 (0.46) | KDM4EALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL9170938 | 0.86 | NPSR1 (0.45) | KDM4EALDH1A1HPGDKAT2BDGAT2 | |
| SCHEMBL9169841 | 0.84 | PDE4A (0.58) | KDM4EALDH1A1KAT2BDGAT2PDE4A | |
| SCHEMBL9172942 | 0.84 | NPSR1 (0.45) | KDM4EALDH1A1HPGDKAT2BPDE4A | |
| SCHEMBL9168148 | 0.83 | NPSR1 (0.43) | KDM4EALDH1A1ABCG2KAT2BPDE4A | |
| SCHEMBL9165637 | 0.83 | NPSR1 (0.56) | KDM4EALDH1A1HPGDKAT2BPDE4A | |
| SCHEMBL9171183 | 0.83 | NPSR1 (0.58) | KDM4EALDH1A1ABCG2KAT2BPDE4A | |
| SCHEMBL9167134 | 0.82 | ALOX5 (0.49) | KDM4EALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL9165629 | 0.82 | NPSR1 (0.62) | KDM4EALDH1A1ABCG2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | claimed |
| US-5405826-A | Herbicidal pyridopyridazinones and pyridopyridazinethiones | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-04-11 | — | — | US | disclosed |
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | disclosed |