Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175449 | 0.95 | TDP1 (0.54) | KEAP1TDP1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL3551020 | 0.86 | KDM4E (0.50) | KMT2ANPSR1 | |
| SCHEMBL28245148 | 0.84 | KDM4E (0.49) | KMT2ANPSR1 | |
| SCHEMBL28372522 | 0.83 | MEN1 (0.55) | KMT2ANPSR1 | |
| SCHEMBL28373044 | 0.83 | KDM4E (0.55) | KMT2ANPSR1 | |
| SCHEMBL28372524 | 0.82 | KDM4E (0.54) | KMT2ANPSR1 | |
| SCHEMBL28366845 | 0.82 | KDM4E (0.54) | KMT2ANPSR1 | |
| SCHEMBL28884842 | 0.82 | KDM4E (0.54) | KMT2ANPSR1 | |
| SCHEMBL7528605 | 0.80 | TSHR (0.54) | TDP1KMT2A | |
| Phenyl Propionic Acid SCHEMBL9656729 | 0.79 | L3MBTL1 (0.44) | KEAP1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492940-B1 | Process for producing and purifying 3,4-dihydrocoumarin | SUMITOMO CHEMICAL CO (JP) | 1995-07-12 | — | — | EP | claimed |
| US-5218129-A | Cyclization, dehydrogenation of a 3-(2-cyclohexanoyl)propionic ester | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | claimed |
| EP-0492940-A1 | Process for producing and purifying 3,4-dihydrocoumarin | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-07-01 | — | — | EP | claimed |
| EP-0492940-B1 | Process for producing and purifying 3,4-dihydrocoumarin | SUMITOMO CHEMICAL CO (JP) | 1995-07-12 | — | — | EP | disclosed |
| US-5218129-A | Cyclization, dehydrogenation of a 3-(2-cyclohexanoyl)propionic ester | SUMITOMO CHEMICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0492940-A1 | Process for producing and purifying 3,4-dihydrocoumarin | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-07-01 | — | — | EP | disclosed |