SCHEMBL9176149

SCHEMBL9176149

O=C(O)Oc1cccc2c1NCCC2

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.62
SLC13A5 Q86YT5 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
PARP1 P09874 1/20 0.37
RXRB P28702 5/20 0.35
RXRA P19793 4/20 0.35
RXRG P48443 3/20 0.35
HDAC4 P56524 1/20 0.35
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
F2 P00734 1/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10771050 0.90 SRC (0.50) SRCSLC13A5MAPTPARP1RXRB
SCHEMBL28092163 0.86 SRC (0.61) SRCSLC13A5KDM4EPARP1
SCHEMBL29941337 0.77 SRC (1.00) SRCSLC13A5KDM4EPARP1ADORA2A
SCHEMBL2333682 0.77 SRC (0.60) SRCPARP1
SCHEMBL16973923 0.77 SRC (0.57) SRCSLC13A5KDM4EMAPTPARP1
SCHEMBL9667559 0.76 SRC (0.49) SRCKDM4EMAPT
SCHEMBL9181326 0.76 SRC (0.40) SRCKDM4EMAPTHDAC4
SCHEMBL30647012 0.76 SRC (0.51) SRCSLC13A5KDM4EMAPTHDAC4
SCHEMBL1520555 0.76 SRC (0.51) SRCSLC13A5KDM4EMAPTHDAC4
SCHEMBL7029485 0.75 SRC (0.58) SRCSLC13A5PARP1ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0310096-B1 Novel cyclic anthranilic acid derivatives and process for their preparation KYORIN SEIYAKU KK (JP) 1995-04-19 EP claimed