Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333682 | 0.80 | SRC (0.60) | SRCPARP1RENHCRTR1HCRTR2 | |
| SCHEMBL28092163 | 0.77 | SRC (0.61) | SRCPARP1SLC13A5 | |
| SCHEMBL11167058 | 0.77 | PARP1 (0.39) | SRCPARP1CA12CA1CA2 | |
| SCHEMBL10909385 | 0.76 | SRC (0.56) | SRCPARP1REN | |
| SCHEMBL18355372 | 0.76 | SRC (0.56) | SRCPARP1F2RENSLC13A5 | |
| SCHEMBL10911476 | 0.76 | SRC (0.56) | SRCPARP1REN | |
| SCHEMBL22341683 | 0.76 | SRC (0.37) | SRCF2CA12CA1CA2 | |
| SCHEMBL9958134 | 0.76 | RXRA (0.43) | — | |
| SCHEMBL9176149 | 0.75 | SRC (0.62) | SRCPARP1F2SLC13A5ADORA2A | |
| SCHEMBL29941337 | 0.74 | SRC (1.00) | SRCPARP1SLC13A5ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317445-A2 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS | ANORMED INC. (CA) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002022600-A2 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS | ANORMED INC. (CA) | 2002-03-21 | — | — | WO | disclosed |