Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916625 | 0.86 | SLC6A2 (0.39) | SLC6A4SLC6A2SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL915774 | 0.86 | KMT2A (0.42) | SLC6A4SLC6A2SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL915354 | 0.86 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL916541 | 0.85 | MAPK1 (0.42) | SLC6A4SLC6A2SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL917614 | 0.83 | SMN1; SMN2 (0.39) | SLC6A4ALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL916561 | 0.83 | SLC6A2 (0.39) | SLC6A4SLC6A2SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL915440 | 0.83 | MAPT (0.39) | SLC6A4SLC6A2SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL916198 | 0.82 | SLC6A2 (0.39) | SLC6A4SLC6A2SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL915683 | 0.82 | ALDH1A1 (0.41) | SLC6A4SLC6A2SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL916219 | 0.82 | ALDH1A1 (0.47) | SLC6A4SLC6A2SLC6A3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009428-A1 | NOVEL ANDROGENS | N.V. ORGANON (NL) | 2011-01-13 | — | — | US | disclosed |
| EP-1742912-B1 | NOVEL ANDROGENS | ORGANON NV (NL) | 2010-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009428-A1 | NOVEL ANDROGENS | NR5A1, AR, NR3C2 | SLC6A4 582/4885SLC6A2 1378/4885SLC6A3 734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.