Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.65 |
| ▸ | PPARG | P37231 | 15/20 | 0.62 |
| ▸ | PPARA | Q07869 | 14/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9091545 | 0.91 | FFAR1 (0.64) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL9090937 | 0.91 | FFAR1 (0.64) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL9258855 | 0.88 | FFAR1 (0.67) | FFAR1PPARGPPARAKDR | |
| SCHEMBL8686656 | 0.83 | PPARG (0.69) | PPARGPPARA | |
| SCHEMBL14310788 | 0.82 | FFAR1 (0.70) | FFAR1PPARGPPARA | |
| SCHEMBL5403576 | 0.81 | FFAR1 (0.79) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL9091592 | 0.81 | FFAR1 (0.69) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6156630 | 0.80 | FFAR1 (0.71) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL9253284 | 0.79 | PPARG (0.55) | FFAR1PPARGPPARAMAPT | |
| SCHEMBL3281065 | 0.79 | KDR (0.76) | FFAR1PPARGPPARAKDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468760-A | Treating atherosclerosis, inflammation, and asthma | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |