Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.67 |
| ▸ | PPARG | P37231 | 17/20 | 0.62 |
| ▸ | PPARA | Q07869 | 16/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8859196 | 0.91 | PPARG (0.72) | PPARGPPARA | |
| SCHEMBL9174135 | 0.89 | KDR (0.69) | FFAR1PPARGPPARAKDR | |
| SCHEMBL9176157 | 0.88 | FFAR1 (0.65) | FFAR1PPARGPPARAKDR | |
| SCHEMBL9174529 | 0.87 | PPARG (0.59) | FFAR1PPARGPPARAKDR | |
| SCHEMBL9259822 | 0.87 | FFAR1 (0.52) | FFAR1PPARGPPARA | |
| SCHEMBL9263906 | 0.87 | PPARG (0.55) | FFAR1PPARGPPARA | |
| SCHEMBL9091545 | 0.87 | FFAR1 (0.64) | FFAR1PPARGPPARAKDR | |
| SCHEMBL9090937 | 0.87 | FFAR1 (0.64) | FFAR1PPARGPPARAKDR | |
| SCHEMBL9259825 | 0.86 | PPARG (0.53) | FFAR1PPARGPPARA | |
| SCHEMBL9259819 | 0.85 | FFAR1 (0.49) | FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459154-A | Enzyme inhibitors as antiinflammatory agents and treatment of atherosclerosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-17 | — | — | US | claimed |
| US-5459154-A | Enzyme inhibitors as antiinflammatory agents and treatment of atherosclerosis | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |