Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 12/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | CYP21A2 | P08686 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9173992 | 1.00 | CYP1B1 (0.44) | CYP1B1POLBMAPTCYP17A1CYP19A1 | |
| SCHEMBL9174332 | 0.85 | MAPT (0.44) | POLBMAPTCYP19A1PGRAR | |
| SCHEMBL9178008 | 0.85 | POLB (0.48) | POLBMAPTCYP19A1PGRCYP3A4 | |
| SCHEMBL8653911 | 0.85 | MAPT (0.48) | POLBMAPTCYP19A1PGRAR | |
| SCHEMBL9179142 | 0.85 | POLB (0.44) | POLBMAPTCYP19A1PGRCYP3A4 | |
| SCHEMBL9174016 | 0.83 | MAPT (0.42) | CYP1B1POLBMAPTCYP19A1PGR | |
| SCHEMBL8653835 | 0.83 | MAPT (0.46) | POLBMAPTCYP19A1PGRCYP3A4 | |
| SCHEMBL9175172 | 0.83 | MAPT (0.46) | POLBMAPTCYP19A1PGRAR | |
| SCHEMBL9177360 | 0.83 | POLB (0.46) | POLBMAPTCYP19A1CYP3A4 | |
| SCHEMBL9178326 | 0.82 | POLB (0.46) | POLBMAPTCYP19A1PGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405979-A | Stereoselectively reducing phenyl-substituted estradiene with electropositive metal in electron-solvating solvent, cleaving ketone protective group with acid | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | disclosed |
| EP-0532562-B1 | PROCESS FOR PRODUCING 10$g(b)-H-STEROIDS | SCHERING AG (DE) | 1994-11-23 | — | — | EP | disclosed |
| WO-1991018918-A1 | PROCESS FOR PRODUCING 10β-H-STEROIDS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-12-12 | — | — | WO | disclosed |