Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177756 | 1.00 | MAPT (0.49) | MAPTPDK2PDE3BPDE3AKCNMA1 | |
| SCHEMBL9176475 | 0.97 | MAPT (0.47) | MAPTPDK2PDE3BPDE3AKCNMA1 | |
| SCHEMBL16648433 | 0.87 | MAPT (0.61) | MAPTPDK2PDE3BPDE3AKCNMA1 | |
| SCHEMBL9173908 | 0.86 | PANK3 (0.46) | MAPTCHRM4CTSSCTSKTACR3 | |
| SCHEMBL9176486 | 0.86 | PANK3 (0.46) | MAPTCHRM4CTSSCTSKTACR3 | |
| SCHEMBL9173914 | 0.86 | PANK3 (0.46) | MAPTCHRM4CTSSCTSKTACR3 | |
| SCHEMBL9171138 | 0.83 | MAPT (0.45) | MAPTPDK2KCNMA1CHRM4CTSS | |
| SCHEMBL9171142 | 0.83 | MAPT (0.45) | MAPTPDK2KCNMA1CHRM4CTSS | |
| SCHEMBL9171300 | 0.82 | OPRM1 (0.48) | MAPTPDK2CHRM4FFAR2CCR5 | |
| SCHEMBL9173069 | 0.82 | MAPT (0.43) | MAPTPDK2PDE3BPDE3AKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442064-A | Anticoagulants, antiagglomerants | DR. KARL THOMAE GMBH (DE) | 1995-08-15 | — | — | US | disclosed |
| EP-0592949-A2 | N-(aminocarbonyl)-piperidines/pepirazines as aggregation inhibiting agents | Dr. Karl Thomae GmbH (DE) | 1994-04-20 | — | — | EP | disclosed |