SCHEMBL9177992

SCHEMBL9177992

CCCCCC(C)(C)c1cc(N=Nc2ccccc2[N+](=O)[O-])c(O)c(C(C)(C)CCCCC)c1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.39
ACHE P22303 2/20 0.39
CES1 P23141 2/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
PTPN11 Q06124 4/20 0.37
PLAU P00749 1/20 0.37
CNR1 P21554 7/20 0.36
CNR2 P34972 7/20 0.36
GPR18 Q14330 3/20 0.35
GPR55 Q9Y2T6 3/20 0.35
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.35
PTPN1 P18031 1/20 0.35
PTPN6 P29350 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11237715 0.92 CES2 (0.39) CES2ACHECES1NPC1RAB9A
SCHEMBL9008430 0.92 CES2 (0.39) CES2ACHECES1NPC1RAB9A
SCHEMBL7702558 0.91 CNR1 (0.39) CES2ACHECES1NPC1RAB9A
SCHEMBL11876492 0.89 NPC1 (0.38) CES2ACHECES1NPC1RAB9A
SCHEMBL9183035 0.87 PSEN1 (0.33) CNR1CNR2CYP1A2
SCHEMBL5184502 0.86 CES2 (0.43) CES2ACHECES1NPC1RAB9A
SCHEMBL5184498 0.86 CES2 (0.43) CES2ACHECES1NPC1RAB9A
SCHEMBL7698053 0.85 CNR1 (0.42) NPC1RAB9APTPN11CNR1CNR2
SCHEMBL9007277 0.85 CNR1 (0.45) CES2ACHECES1NPC1RAB9A
SCHEMBL9177988 0.85 NPC1 (0.41) CES2ACHECES1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034836-B1 PROCESS FOR PREPARING NITROAZO BENZENES CIBA-GEIGY AG (CH) 1983-07-13 EP claimed
US-4275004-A High caustic coupling process for preparing substituted 2-nitro-2'-hydroxyazobenzenes CIBA-GEIGY CORPORATION (US) 1981-06-23 US claimed
EP-0006564-A2 2-(3.5-disubstituted-2-hydroxyphenyl)-2H-benzotriazoles and stabilized compositions containing them CIBA-GEIGY AG (CH) 1980-01-09 EP claimed
EP-0380840-B1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA LTD (JP) 1995-05-17 EP disclosed
US-5187289-A Method of preparing 2-phenyl benzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1993-02-16 US disclosed
EP-0263905-B1 METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES CHEMIPRO KASEI KAISHA, LTD. (JP) 1992-04-15 EP disclosed
US-5104992-A METHOD OF PREPARING 2-PHENYL BENEZOTHRIAZOLES CHEMIPRO KASEI KAISHA, LTD. (JP) 1992-04-14 US disclosed
EP-0380840-A1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-08-08 EP disclosed
EP-0380839-A1 Method of preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-08-08 EP disclosed
US-4943637-A Method for preparing 2-phenylbenzotriazoles CHEMIPRO KASEI KAISHA, LTD. (JP) 1990-07-24 US disclosed
EP-0160246-B1 A METHOD FOR PRODUCING A 2-PHENYLBENZOTRIAZOLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-01-24 EP disclosed
US-4835284-A Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1989-05-30 US disclosed
EP-0263905-A1 Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides CHEMIPRO KASEI KAISHA, LTD. (JP) 1988-04-20 EP disclosed
EP-0160246-A1 A method for producing A 2-phenylbenzotriazole SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-06 EP disclosed
US-4477614-A FOR POLYAMIDES CIBA-GEIGY CORPORATION (US) 1984-10-16 US disclosed
US-4447511-A PREVENTION IMAGE DEGRADATION DUE TO ULTRAVIOLET LIGHT CIBA-GEIGY CORPORATION (US) 1984-05-08 US disclosed
US-4383863-A 2-[2-Hydroxy-3,5-di-tert-octylphenyl]-2H-benzotriazole in stabilized photographic compositions CIBA-GEIGY CORPORATION (US) 1983-05-17 US disclosed
US-4283327-A USED AS A LIGHT STABILIZER CIBA-GEIGY CORPORATION (US) 1981-08-11 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed