SCHEMBL91780

SCHEMBL91780

Cc1ccc2cc(-c3ccc(-c4c(C)cc(C5CCC(C)CO5)cc4C)cc3)ccc2c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
ABL1 P00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91769 0.90 MAOB (0.32)
SCHEMBL91905 0.83 ESR1 (0.33) ABL1
SCHEMBL91788 0.82 KMT2A (0.40) CYP1A2
SCHEMBL91778 0.82
SCHEMBL91738 0.81 HSD11B1 (0.37)
SCHEMBL18800276 0.80 CYP2A6 (0.41) CYP1A2CYP2A6
SCHEMBL91737 0.79 HSD11B1 (0.33)
SCHEMBL91772 0.79
SCHEMBL91816 0.77 KMT2A (0.39) CYP1A2
SCHEMBL91755 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129002-B2 Compounds for use in liquid crystal media MERCK PATENT GMBH (DE) 2012-03-06 US disclosed