Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178115 | 1.00 | TP53 (0.54) | TP53TSHRL3MBTL1MAPTNPY1R | |
| SCHEMBL7488989 | 0.85 | TP53 (0.55) | TP53TSHRL3MBTL1MAPTMEN1 | |
| SCHEMBL7488984 | 0.85 | TP53 (0.55) | TP53TSHRL3MBTL1MAPTMEN1 | |
| SCHEMBL8327933 | 0.85 | TP53 (0.55) | TP53TSHRL3MBTL1MAPTMEN1 | |
| SCHEMBL8562162 | 0.85 | TP53 (0.55) | TP53TSHRL3MBTL1MAPTMEN1 | |
| SCHEMBL7497190 | 0.84 | TP53 (0.61) | TP53TSHRL3MBTL1MAPTMEN1 | |
| SCHEMBL7497183 | 0.84 | TP53 (0.61) | TP53TSHRL3MBTL1MAPTMEN1 | |
| SCHEMBL11442173 | 0.81 | TP53 (0.52) | TP53TSHRL3MBTL1MAPTMEN1 | |
| SCHEMBL11442176 | 0.81 | TP53 (0.52) | TP53TSHRL3MBTL1MAPTMEN1 | |
| SCHEMBL26188640 | 0.76 | MAPT (0.47) | TSHRL3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468750-A | Antiinflammatory agents and autoimmune diseases | ELF SANOFI (FR) | 1995-11-21 | — | — | US | disclosed |
| US-5360799-A | Free radical inhibitors | ELF SANOFI (FR) | 1994-11-01 | — | — | US | disclosed |