Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178120 | 0.85 | TP53 (0.54) | TP53L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL9178115 | 0.85 | TP53 (0.54) | TP53L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL9635849 | 0.74 | MAPT (0.47) | L3MBTL1TSHRMEN1KMT2ARAB9A | |
| SCHEMBL15271139 | 0.74 | TP53 (0.67) | TP53L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL15271141 | 0.74 | TP53 (0.67) | TP53L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL15278966 | 0.74 | TP53 (0.67) | TP53L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL7281443 | 0.72 | RAB9A (0.52) | TP53L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL7281436 | 0.72 | RAB9A (0.52) | TP53L3MBTL1MEN1KMT2ARAB9A | |
| SCHEMBL14906007 | 0.71 | MAPT (0.57) | TP53L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL8327933 | 0.70 | TP53 (0.55) | TP53L3MBTL1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587473-B1 | Condensed pyridine derivatives as inhibitors of the effects of free radicals | SANOFI SA (FR) | 1998-11-11 | — | — | EP | disclosed |
| EP-0587473-A1 | Condensed pyridine derivatives as inhibitors of the effects of free radicals | SANOFI (FR) | 1994-03-16 | — | — | EP | disclosed |