Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176375 | 0.84 | ELANE (0.54) | ELANEKDM1ACA2ESR1HIF1A | |
| SCHEMBL9179232 | 0.82 | ELANE (0.55) | ELANEKDM1AESR1HIF1A | |
| SCHEMBL8781783 | 0.80 | ELANE (0.60) | ELANEKDM1ACA2ESR1HIF1A | |
| SCHEMBL197026 | 0.79 | ELANE (0.55) | ELANEKDM1AHTR2APPARGPPARA | |
| SCHEMBL196293 | 0.78 | ELANE (0.66) | ELANEKDM1APPARGPPARACA2 | |
| SCHEMBL197179 | 0.78 | ELANE (0.66) | ELANEKDM1ACA2ESR1HIF1A | |
| SCHEMBL9171373 | 0.78 | ELANE (0.57) | ELANEKDM1ACA2ESR1HIF1A | |
| SCHEMBL9178617 | 0.78 | ELANE (0.47) | ELANEPPARGPPARAESR1 | |
| SCHEMBL4061370 | 0.78 | ELANE (0.81) | ELANEKDM1ACA2 | |
| SCHEMBL4056333 | 0.77 | ELANE (0.64) | ELANEKDM1ARXRARXRBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525626-B1 | Compounds containing acid-cleavable protective groups and positive-working radiation-sensitive compositions prepared using these compounds | HOECHST AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| US-5356752-A | Compounds with acid-labile protective groups useful in positive-working radiation-sensitive mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| EP-0525626-A1 | Compounds containing acid-cleavable protective groups and positive-working radiation-sensitive compositions prepared using these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-03 | — | — | EP | disclosed |