Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176375 | 0.94 | ELANE (0.54) | ELANEKDM1AFAAHESR1HIF1A | |
| SCHEMBL9178128 | 0.82 | ELANE (0.53) | ELANEKDM1AESR1HIF1A | |
| SCHEMBL9178617 | 0.82 | ELANE (0.47) | ELANEFAAHESR1L3MBTL1 | |
| SCHEMBL9176365 | 0.81 | ELANE (0.46) | ELANEKDM1ASMN1; SMN2 | |
| SCHEMBL8781783 | 0.79 | ELANE (0.60) | ELANEKDM1ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL4061308 | 0.78 | ELANE (0.49) | ELANEFAAHMAPK1L3MBTL1 | |
| SCHEMBL9175757 | 0.78 | THRA (0.40) | ELANEESR1 | |
| SCHEMBL197179 | 0.77 | ELANE (0.66) | ELANEKDM1AESR1HIF1AMAPKAPK2 | |
| SCHEMBL5701486 | 0.77 | ELANE (0.57) | ELANEKDM1ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL9171373 | 0.77 | ELANE (0.57) | ELANEKDM1ASMN1; SMN2ESR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525626-B1 | Compounds containing acid-cleavable protective groups and positive-working radiation-sensitive compositions prepared using these compounds | HOECHST AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0525626-A1 | Compounds containing acid-cleavable protective groups and positive-working radiation-sensitive compositions prepared using these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-03 | — | — | EP | disclosed |