Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 0.66 |
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.66 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9180015 | 0.90 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1CTSDLMNACYP1A2 | |
| SCHEMBL9281892 | 0.88 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9172468 | 0.87 | LMNA (0.68) | CYSLTR2CYSLTR1CTSDLMNACYP1A2 | |
| SCHEMBL9638148 | 0.87 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1CTSDLMNACYP1A2 | |
| SCHEMBL9638144 | 0.85 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1CTSDLMNACYP1A2 | |
| SCHEMBL9637077 | 0.85 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1CTSDLMNACYP1A2 | |
| SCHEMBL9173547 | 0.85 | GRM2 (0.68) | CYSLTR2CYSLTR1CTSDLMNACYP1A2 | |
| SCHEMBL9177294 | 0.84 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9177346 | 0.83 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9176107 | 0.82 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393768-A | Treating hypersensitivity reactions such as asthma | ELI LILLY AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5105017-A | Antiallergens | ELI LILLY AND COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0132366-A2 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |