Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170767 | 0.84 | CTSD (0.47) | CTSDKDM4EMAPTALOX15MAPK1 | |
| SCHEMBL7974622 | 0.82 | CYSLTR2 (0.47) | MAPTLMNACYSLTR2CYSLTR1 | |
| SCHEMBL2862125 | 0.80 | MAPT (0.49) | CTSDTSHRKDM4EMAPTALOX15 | |
| SCHEMBL9175493 | 0.77 | HTT (0.40) | MAPTALDH1A1CYSLTR2CYSLTR1 | |
| SCHEMBL1446427 | 0.77 | BCL2 (0.50) | KDM4EMAPTALOX15MAPK1HSD17B10 | |
| SCHEMBL3070364 | 0.76 | TYR (0.44) | CTSDKDM4EMAPTALOX15MAPK1 | |
| SCHEMBL2868258 | 0.76 | HPGD (0.47) | TSHRKDM4EMAPTALOX15MAPK1 | |
| SCHEMBL9175489 | 0.76 | CTSD (0.61) | CTSDKDM4EMAPTALOX15HSD17B10 | |
| SCHEMBL2855431 | 0.75 | PPARG (0.46) | CTSDKDM4EMAPTALOX15MAPK1 | |
| SCHEMBL29236376 | 0.75 | BCL2 (0.49) | CTSDKDM4EMAPTALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393768-A | Treating hypersensitivity reactions such as asthma | ELI LILLY AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5105017-A | Antiallergens | ELI LILLY AND COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0132366-B1 | LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| EP-0132366-A2 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |