Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201165 | 0.88 | CYP2D6 (0.56) | CYP2D6NR1I2CYP3A4HCAR2VHL | |
| SCHEMBL8875268 | 0.88 | CYP2D6 (0.56) | CYP2D6NR1I2CYP3A4HCAR2VHL | |
| SCHEMBL9863164 | 0.88 | NR1I2 (0.46) | CYP2D6NR1I2CYP3A4HCAR2VHL | |
| SCHEMBL8875953 | 0.87 | NR1I2 (0.55) | CYP2D6NR1I2CYP3A4VHLMEN1 | |
| SCHEMBL10413141 | 0.87 | PLAU (0.51) | CYP2D6NR1I2CYP3A4HCAR2VHL | |
| SCHEMBL9706268 | 0.87 | NR1I2 (0.45) | CYP2D6NR1I2CYP3A4HCAR2PLA2G2A | |
| SCHEMBL9209739 | 0.86 | NR1I2 (0.54) | CYP2D6NR1I2CYP3A4VHLMEN1 | |
| SCHEMBL9202726 | 0.84 | CYP2D6 (0.51) | CYP2D6NR1I2CYP3A4HCAR2VHL | |
| SCHEMBL9208970 | 0.83 | NR1I2 (0.51) | CYP2D6NR1I2CYP3A4VHLMEN1 | |
| SCHEMBL9862923 | 0.83 | NR1I2 (0.45) | CYP2D6NR1I2CYP3A4HCAR2VHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5110821-A | Picornavirus | STERLING DRUG INC. (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |