Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875953 | 0.89 | NR1I2 (0.55) | NR1I2CYP3A4CYP2D6RAB9AMEN1 | |
| SCHEMBL10413619 | 0.88 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6RAB9ATDP1 | |
| SCHEMBL9178754 | 0.86 | CYP2D6 (0.57) | NR1I2CYP3A4CYP2D6RAB9ABRD4 | |
| SCHEMBL9201165 | 0.85 | CYP2D6 (0.56) | NR1I2CYP3A4CYP2D6RAB9AMEN1 | |
| SCHEMBL8875268 | 0.85 | CYP2D6 (0.56) | NR1I2CYP3A4CYP2D6RAB9AMEN1 | |
| SCHEMBL8875936 | 0.85 | NR1I2 (0.62) | NR1I2CYP3A4CYP2D6RAB9ATDP1 | |
| SCHEMBL8874325 | 0.82 | NR1I2 (0.48) | NR1I2CYP3A4CYP2D6RAB9ATDP1 | |
| SCHEMBL9202726 | 0.81 | CYP2D6 (0.51) | NR1I2CYP3A4CYP2D6RAB9AMEN1 | |
| SCHEMBL5884654 | 0.80 | NR1I2 (0.51) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL9208970 | 0.80 | NR1I2 (0.51) | NR1I2CYP3A4CYP2D6RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413289-B1 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5110821-A | Picornavirus | STERLING DRUG INC. (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0413289-A2 | Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1991-02-20 | — | — | EP | disclosed |