SCHEMBL9180130

SCHEMBL9180130

NCCCC[C@H](NC(=O)CN)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)NCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ SLC15A2 Q16348 1/20 0.52
▸ CALCRL Q16602 2/20 0.39
▸ NMT1 P30419 6/20 0.37
▸ NMT2 O60551 5/20 0.37
▸ GHSR Q92847 1/20 0.36
▸ ROCK2 O75116 1/20 0.35
▸ PSMB1 P20618 1/20 0.34
▸ PSMB8 P28062 1/20 0.34
▸ PSMB9 P28065 1/20 0.34
▸ PSMB5 P28074 1/20 0.34
▸ PSMB10 P40306 1/20 0.34
▸ PSMB2 P49721 1/20 0.34
▸ F2 P00734 1/20 0.34
▸ MMP1 P03956 1/20 0.34
▸ CHRNA1 P02708 1/20 0.33
▸ CHRNG P07510 1/20 0.33
▸ CHRNB1 P11230 1/20 0.33
▸ CHRND Q07001 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29746001 0.92 SLC15A2 (0.57) SLC15A2CALCRLNMT1NMT2GHSR
SCHEMBL3357272 0.91 SLC15A2 (0.42) SLC15A2CALCRLPSMB1PSMB8PSMB9
SCHEMBL3357251 0.91 SLC15A2 (0.42) SLC15A2CALCRLPSMB1PSMB8PSMB9
SCHEMBL29484171 0.90 SLC15A2 (0.41) SLC15A2CALCRLGHSRPSMB1PSMB8
SCHEMBL29473319 0.90 SLC15A2 (0.63) SLC15A2CALCRLGHSR
SCHEMBL259179 0.90 SLC15A2 (0.38) SLC15A2
SCHEMBL259178 0.90 SLC15A2 (0.38) SLC15A2
SCHEMBL6116135 0.90 SLC15A2 (0.41) SLC15A2CALCRLPSMB1PSMB8PSMB9
SCHEMBL6116125 0.90 SLC15A2 (0.41) SLC15A2CALCRLPSMB1PSMB8PSMB9
SCHEMBL1526024 0.89 SLC15A2 (0.54) SLC15A2CALCRLNMT1NMT2GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0489860-B1 METHODS AND COMPOSITIONS FOR HEALING ULCERS PROCYTE CORP (US) 1995-08-02 — — EP disclosed
EP-0495877-B1 METHODS AND COMPOSITIONS FOR HEALING BONE PROCYTE CORP (US) 1995-03-22 — — EP disclosed
US-5145838-A Peptide derivatives PROCYTE CORPORATION (US) 1992-09-08 — — US disclosed
EP-0495877-A1 METHODS AND COMPOSITIONS FOR HEALING BONE. PROCYTE CORP (US) 1992-07-29 — — EP disclosed
US-5059588-A METHODS AND COMPOSITIONS FOR HEALING BONE USING GLY HIS LYS: COPPER PROCYTE CORPORATION, INCORPORATED (US) 1991-10-22 — — US disclosed
US-5023237-A Using oligopeptide containing glycine, histidine, and lysine PROCYTE CORPORATION (US) 1991-06-11 — — US disclosed
WO-1991005797-A1 METHODS AND COMPOSITIONS FOR HEALING BONE PROCYTE CORPORATION (US) 1991-05-02 — — WO disclosed
Send feedback