Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 1.00 |
| ▸ | NPC1 | O15118 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | STAT3 | P40763 | 1/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.68 |
| ▸ | RELA | Q04206 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | CASP3 | P42574 | 2/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | ESR1 | P03372 | 2/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283948 | 1.00 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL7752727 | 1.00 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL10685934 | 1.00 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL8025073 | 1.00 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9326045 | 0.98 | RAB9A (0.97) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9326013 | 0.98 | RAB9A (0.97) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL10459672 | 0.98 | RAB9A (0.97) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL7789917 | 0.97 | RAB9A (0.94) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL21816567 | 0.94 | RAB9A (0.88) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9329063 | 0.92 | RAB9A (0.86) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482024-B1 | CHIRAL OR ACHIRAL RING COMPOUNDS | MERCK PATENT GMBH (DE) | 1995-05-24 | — | — | EP | disclosed |
| EP-0482024-A1 | CHIRAL OR ACHIRAL RING COMPOUNDS. | MERCK PATENT GMBH (DE) | 1992-04-29 | — | — | EP | disclosed |
| EP-0239403-B1 | 2-(4'-ALKOXYPHENYL)-5-ALKYLPYRIDINES | Chisso Corporation (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-5055222-A | Enantiomorph for use in liquid crystal display elements | CHISSO CORPORATION (JP) | 1991-10-08 | — | — | US | disclosed |
| WO-1991000897-A1 | CHIRAL OR ACHIRAL RING COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-01-24 | — | — | WO | disclosed |
| US-4795587-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1989-01-03 | — | — | US | disclosed |
| US-4752413-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1988-06-21 | — | — | US | disclosed |
| EP-0267758-A2 | Alpha-substituted-propionic acid esters | Chisso Corporation (JP) | 1988-05-18 | — | — | EP | disclosed |
| EP-0247804-A2 | 2-(Alkyloxycarbonyloxyphenyl)-5-alkylpyridine and composition containing same | Chisso Corporation (JP) | 1987-12-02 | — | — | EP | disclosed |
| EP-0239403-A1 | 2-(4'-Alkoxyphenyl)-5-alkylpyridines | Chisso Corporation (JP) | 1987-09-30 | — | — | EP | disclosed |