Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.57 |
| ▸ | PPARA | Q07869 | 14/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157414 | 0.90 | KDR (0.67) | PPARGPPARAKDRCYP2C9KCNH2 | |
| SCHEMBL8545784 | 0.86 | PPARG (0.55) | PPARGPPARAKDRCYP2C9KCNH2 | |
| SCHEMBL9178784 | 0.86 | PPARG (0.54) | PPARGPPARAKDRCYP2C9KCNH2 | |
| SCHEMBL9178780 | 0.86 | PPARG (0.54) | PPARGPPARAKDRCYP2C9KCNH2 | |
| SCHEMBL13144923 | 0.83 | PPARG (0.52) | PPARGPPARAKDRCYP2C9KCNH2 | |
| SCHEMBL3081643 | 0.82 | PPARG (0.58) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL7563293 | 0.81 | KDR (0.60) | PPARGPPARAKDRMAPT | |
| SCHEMBL6960376 | 0.80 | KDR (0.63) | PPARGPPARAKDRCYP2C9KCNH2 | |
| SCHEMBL6960372 | 0.80 | KDR (0.63) | PPARGPPARAKDRCYP2C9KCNH2 | |
| SCHEMBL9179359 | 0.80 | PPARG (0.55) | PPARGPPARAKDRCYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468760-A | Treating atherosclerosis, inflammation, and asthma | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |