Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186890 | 0.90 | DDAH1 (0.45) | DDAH1ADRA2CALDH1A1RAB9AKMT2A | |
| SCHEMBL9186860 | 0.86 | DDAH1 (0.43) | DDAH1ADRA2CALDH1A1RAB9AKMT2A | |
| SCHEMBL9182391 | 0.86 | DDAH1 (0.43) | DDAH1ADRA2CRAB9AMAPK1TDP1 | |
| SCHEMBL9184518 | 0.85 | MAPT (0.44) | DDAH1ADRA2CALDH1A1RAB9AKMT2A | |
| SCHEMBL9181930 | 0.85 | TP53 (0.44) | DDAH1ADRA2CALDH1A1KMT2AMEN1 | |
| SCHEMBL9184408 | 0.83 | DDAH1 (0.41) | DDAH1ADRA2CALDH1A1RAB9AKMT2A | |
| SCHEMBL9187542 | 0.81 | MAPT (0.42) | DDAH1ADRA2CALDH1A1RAB9AKMT2A | |
| SCHEMBL9187035 | 0.81 | HPGD (0.46) | DDAH1ADRA2CALDH1A1RAB9AKMT2A | |
| SCHEMBL9183582 | 0.81 | DDAH1 (0.39) | DDAH1ADRA2CALDH1A1RAB9AKMT2A | |
| SCHEMBL7624296 | 0.81 | DDAH1 (0.60) | DDAH1ADRA2CALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451594-A | NEMATOCIDES, INSECTICIDES, MITICIDES AND FUNGICIDES | ZENECA LIMITED (GB) | 1995-09-19 | — | — | US | disclosed |
| EP-0660830-A1 | BENZOXAZOLE AND BEZOTHIAZOLE DERIVATIVES | ZENECA LIMITED (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006782-A1 | BENZOXAZOLE AND BEZOTHIAZOLE DERIVATIVES | ZENECA LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |