SCHEMBL9181550

SCHEMBL9181550

CC(=O)CC(=O)Nc1cc(Cl)ccc1C

nearest known ligand 0.76

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.69
GAA P10253 2/20 0.69
ALDH1A1 P00352 4/20 0.68
LMNA P02545 3/20 0.68
MEN1 O00255 3/20 0.66
KMT2A Q03164 3/20 0.66
TSHR P16473 2/20 0.64
HTT P42858 2/20 0.62
MAPT P10636 2/20 0.62
SMN1; SMN2 Q16637 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31570088 0.87 KMT2A (0.61) POLBGAAALDH1A1LMNAMEN1
SCHEMBL8824873 0.87 KMT2A (0.61) POLBGAAALDH1A1LMNAMEN1
SCHEMBL9620133 0.85 GAA (0.77) POLBGAAALDH1A1LMNAMEN1
SCHEMBL54924 0.85 MEN1 (0.80) POLBGAAALDH1A1LMNAMEN1
SCHEMBL4005240 0.85 GAA (0.71) POLBGAAALDH1A1LMNAMEN1
SCHEMBL14202808 0.83 POLB (0.69) POLBGAAALDH1A1LMNAMEN1
SCHEMBL1577190 0.83 HDAC3 (0.62) POLBGAAALDH1A1LMNAMEN1
SCHEMBL6106176 0.82 GAA (0.63) POLBGAAALDH1A1LMNAKMT2A
SCHEMBL9180503 0.81 HPGD (0.68) POLBGAAALDH1A1LMNAMEN1
SCHEMBL31590796 0.81 HPGD (0.68) POLBGAAALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4169851-A PROCESS FOR THE MANUFACTURE OF ACETOACETYL-AMINOBENZENES HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-02 US claimed
EP-0001994-A1 Process for preparing acetylaminobenzenes HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-30 EP claimed
EP-0587021-B1 Use of preparations of azo-pigments containing solvents for intaglio printing and flexographic printing on packaging HOECHST AG (DE) 1995-08-16 EP disclosed
US-5352281-A Containing nonionic surfactant with specified cloud point HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-04 US disclosed
EP-0587021-A1 Use of preparations of azo-pigments containing solvents for intaglio printing and flexographic printing on packaging HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-16 EP disclosed
EP-0001994-B1 PROCESS FOR PREPARING ACETYLAMINOBENZENES HOECHST AKTIENGESELLSCHAFT (DE) 1980-09-17 EP disclosed
US-4169851-A PROCESS FOR THE MANUFACTURE OF ACETOACETYL-AMINOBENZENES HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-02 US disclosed
US-4169091-A Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component HOECHST AKTIENGESELLSCHAFT (DE) 1979-09-25 US disclosed
EP-0001994-A1 Process for preparing acetylaminobenzenes HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-30 EP disclosed