SCHEMBL14202808

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9620133	0.85	GAA (0.77)	POLBGAAALDH1A1LMNATSHR
	SCHEMBL4005240	0.85	GAA (0.71)	POLBGAAALDH1A1LMNATSHR
	SCHEMBL9181550	0.83	POLB (0.69)	POLBGAAALDH1A1LMNATSHR
	SCHEMBL7934469	0.83	POLB (0.77)	POLBGAAALDH1A1LMNAMAPT
	SCHEMBL21561682	0.83	HDAC3 (0.62)	POLBALDH1A1LMNASMN1; SMN2MEN1
	SCHEMBL1068813	0.80	GAA (0.65)	POLBGAAALDH1A1LMNATSHR
	SCHEMBL20812868	0.80	LMNA (0.57)	POLBGAAALDH1A1LMNATSHR
	SCHEMBL7936652	0.80	MEN1 (0.53)	POLBGAAALDH1A1LMNAMAPT
	SCHEMBL1509787	0.80	ALDH1A1 (0.51)	POLBGAAALDH1A1HTTMAPT
	SCHEMBL7931375	0.80	KMT2A (0.80)	POLBALDH1A1LMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.