Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 8/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21193197 | 0.83 | HPGD (0.41) | ALDH1A1USP2HPGD | |
| SCHEMBL9177991 | 0.83 | CYP2C9 (0.46) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL9180228 | 0.80 | CYP2C9 (0.44) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL10514286 | 0.80 | USP2 (0.36) | CYP1A2ALDH1A1USP2TSHR | |
| SCHEMBL28520243 | 0.80 | CYP2D6 (0.49) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL12895649 | 0.76 | CYP2C9 (0.51) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL12254227 | 0.75 | CYP2C9 (0.54) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL10514266 | 0.75 | USP2 (0.31) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL29891860 | 0.74 | CYP1A2 (0.65) | CYP2C9CYP1A2CYP2D6ALDH1A1USP2 | |
| SCHEMBL6127950 | 0.74 | SMN1; SMN2 (0.50) | CYP2C9CYP1A2CYP2D6CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453422-A | Animal growth promoters | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| US-5284842-A | Active against gramnegative bacteria | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| US-5173484-A | Animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |