Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174181 | 0.90 | — | — | |
| SCHEMBL1037297 | 0.88 | — | — | |
| SCHEMBL9176472 | 0.86 | — | — | |
| SCHEMBL9180759 | 0.85 | HTR1A (0.63) | HTR1A | |
| SCHEMBL9179406 | 0.84 | HTR1A (0.67) | HTR1A | |
| SCHEMBL9173735 | 0.83 | HTR1A (0.43) | HTR1A | |
| SCHEMBL9466874 | 0.83 | HTR1A (0.43) | HTR1A | |
| SCHEMBL9173732 | 0.83 | HTR1A (0.43) | HTR1A | |
| SCHEMBL9176539 | 0.83 | — | — | |
| SCHEMBL9174162 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490772-B1 | 1,4-Disubstituted piperazines, their process of preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-07-26 | — | — | EP | disclosed |