Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.90 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.90 |
| ▸ | ATM | Q13315 | 1/20 | 0.90 |
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.80 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.80 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL9183225 | 1.00 | KDM4E (0.90) | KDM4EPMP22ATMTSHRNFKB1 | |
| Tetrylammonium SCHEMBL49847 | 0.95 | KDM4E (1.00) | KDM4EPMP22ATMTSHRNFKB1 | |
| Tetrylammonium SCHEMBL10982449 | 0.95 | KDM4E (1.00) | KDM4EPMP22ATMTSHRNFKB1 | |
| Tetrylammonium SCHEMBL9438624 | 0.95 | TSHR (0.89) | KDM4EPMP22ATMTSHRNFKB1 | |
| Tetrylammonium SCHEMBL5374883 | 0.95 | KDM4E (1.00) | KDM4EPMP22ATMTSHRNFKB1 | |
| Tetrylammonium SCHEMBL6560332 | 0.90 | KDM4E (0.90) | KDM4EPMP22ATMTSHRNFKB1 | |
| Tetrylammonium SCHEMBL228998 | 0.90 | KDM4E (0.90) | KDM4EPMP22ATMTSHRNFKB1 | |
| Tetrylammonium SCHEMBL22664597 | 0.90 | KDM4E (0.90) | KDM4EPMP22ATMTSHRNFKB1 | |
| Tetrylammonium SCHEMBL10982446 | 0.90 | KDM4E (0.90) | KDM4EPMP22ATMTSHRNFKB1 | |
| Tetrylammonium SCHEMBL5374887 | 0.90 | KDM4E (0.90) | KDM4EPMP22ATMTSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387708-A | Reacting an alkanol, carbon monoxide and oxygen in vapor phase in the presence of a catalyst containing a copper halide and a quaternary ammonium salt on a support | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |