Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187577 | 0.79 | CHRM2 (0.64) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7755543 | 0.76 | KMT2A (0.69) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9430809 | 0.76 | CHRM1 (1.00) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL4475179 | 0.73 | CHRM1 (0.59) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL15441017 | 0.73 | CHRM1 (0.47) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9459030 | 0.73 | CHRM1 (0.64) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL8654610 | 0.71 | MMP13 (0.44) | — | |
| SCHEMBL9489707 | 0.70 | CHRM1 (0.56) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL9458720 | 0.69 | KMT2A (0.62) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL15448102 | 0.69 | CHRM1 (0.55) | CHRM1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468590-A | Positive resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-11-21 | — | — | US | disclosed |
| EP-0674635-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014803-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |