SCHEMBL9183904

SCHEMBL9183904

CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)CC1S(=O)(=O)CCCS1(=O)=O

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.56
▸ PGC P20142 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10540148 0.89 REN (0.60) RENPGC
SCHEMBL7271925 0.88 REN (0.57) RENPGC
SCHEMBL7386767 0.88 REN (0.57) RENPGC
SCHEMBL9183934 0.88 REN (0.56) RENPGC
SCHEMBL9504686 0.86 REN (0.57) RENPGC
SCHEMBL9694434 0.86 REN (0.57) RENPGC
SCHEMBL9505561 0.86 REN (0.57) RENPGC
SCHEMBL9223307 0.86 REN (0.43) RENPGC
SCHEMBL7272695 0.86 REN (0.56) RENPGC
SCHEMBL7382612 0.86 REN (0.58) RENPGC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0446485-B1 Peptide analogues with renininhibiting activity MERCK PATENT GMBH (DE) 1995-09-06 — — EP claimed
US-5401722-A Peptide analogues MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-03-28 — — US claimed
EP-0509783-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 — — EP disclosed
US-5283227-A With aziridine compound stabilizer OJI PAPER CO., LTD. (JP) 1994-02-01 — — US disclosed
EP-0509783-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1992-10-21 — — EP disclosed
EP-0503856-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1992-09-16 — — EP disclosed
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