SCHEMBL918396

SCHEMBL918396

Oc1cc2ccccc2c(-c2c(O)c(O)cc3ccccc23)c1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.60
ALOX5 P09917 1/20 0.53
NQO2 P16083 1/20 0.52
PTPN22 Q9Y2R2 1/20 0.48
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPT P10636 3/20 0.46
CYP1A2 P05177 2/20 0.46
NQO1 P15559 1/20 0.44
MPL P40238 1/20 0.42
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 3/20 0.42
CYP1B1 Q16678 2/20 0.42
HIF1A Q16665 1/20 0.42
IDO1 P14902 1/20 0.42
CASP6 P55212 1/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 3/20 0.41
TTR P02766 1/20 0.41
CYP1A1 P04798 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381319 1.00 TRPM4 (0.60) TRPM4ALOX5NQO2PTPN22MEN1
SCHEMBL1150949 0.90 MAPT (0.59) TRPM4ALOX5NQO2PTPN22MEN1
SCHEMBL14413583 0.88 LMNA (0.50) TRPM4ALOX5NQO2PTPN22MEN1
SCHEMBL9463316 0.87 TRPM4 (0.52) TRPM4ALOX5NQO2PTPN22MEN1
SCHEMBL888517 0.84 TRPM4 (0.48) TRPM4ALOX5NQO2PTPN22MEN1
SCHEMBL30117593 0.84 TRPM4 (0.48) TRPM4ALOX5NQO2PTPN22MEN1
SCHEMBL29428933 0.84 TRPM4 (0.48) TRPM4ALOX5NQO2PTPN22MEN1
SCHEMBL13678950 0.84 KDM4E (0.53) TRPM4ALOX5NQO2PTPN22MEN1
SCHEMBL27738 0.83 TRPM4 (0.62) TRPM4ALOX5NQO2PTPN22MEN1
SCHEMBL30151482 0.83 TRPM4 (0.62) TRPM4ALOX5NQO2PTPN22MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3031856-B1 CROSSLINKABLE FLUORINATED ELASTOMER COMPOSITION AND CROSSLINKED PRODUCT THEREOFa AGC INC (JP) 2019-07-10 EP claimed
US-10066077-B2 Crosslinkable fluorinated elastomer composition and crosslinked product thereof ASAHI GLASS COMPANY, LIMITED (JP) 2018-09-04 US claimed
EP-3031856-A1 FLUORINE-CONTAINING CROSSLINKABLE ELASTOMER COMPOSITION AND CROSSLINKED PRODUCT THEREOF Asahi Glass Company, Limited (JP) 2016-06-15 EP claimed
US-20160137809-A1 CROSSLINKABLE FLUORINATED ELASTOMER COMPOSITION AND CROSSLINKED PRODUCT THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2016-05-19 US claimed
US-8519080-B2 Crosslinkable prepolymer, its production process and its uses ASAHI GLASS COMPANY, LIMITED (JP) 2013-08-27 US claimed
US-8168742-B2 Crosslinkable fluorinated aromatic prepolymer and its uses ASAHI GLASS COMPANY, LIMITED (JP) 2012-05-01 US claimed
EP-0471498-B1 Optical resolution method KANKYO KAGAKU CENTER (JP) 1997-12-17 EP claimed
JP-10218904-A None JP disclosed
US-20230178848-A1 ELECTRODE SEPARATORS UNIV KING ABDULLAH SCI & TECH (SA) 2023-06-08 US disclosed
US-20230178848-A1 ELECTRODE SEPARATORS UNIV KING ABDULLAH SCI & TECH (SA) 2023-06-08 US disclosed
US-20220219125-A1 HYBRID INORGANIC OXIDE-CARBON MOLECULAR SIEVE MEMBRANES UNIV KING ABDULLAH SCI & TECH (SA) 2022-07-14 US disclosed
EP-3111202-B1 FLEXIBLE SENSOR PATCH AND METHOD OF USING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2021-07-14 EP disclosed
WO-2019218542-A1 MICROPOROUS POLYMER FILM WITH ION CONDUCTIVITY AND PREPARATION METHOD AND APPLICATION THEREOF 天津理工大学 (CN) 2019-11-21 WO disclosed
EP-0934955-A1 Polymerization process characterized by a two layer coating against scale formation deposited using a steam carrier SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-08-11 EP disclosed
JP-H10218904-A POLYMER SCALE INHIBITOR AND PRODUCTION OF VINYL CHLORIDE POLYMER BY USING THE SAME SHIN ETSU CHEM CO LTD 1998-08-18 JP disclosed
EP-0857739-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-08-12 EP disclosed
EP-0471498-B1 Optical resolution method KANKYO KAGAKU CENTER (JP) 1997-12-17 EP disclosed
US-5510520-A Optical resolution method KANKYO KAGAKU CENTER CO., LTD. (JP) 1996-04-23 US disclosed
US-5395962-A Optical resolution method KANKYO KAGAKU CENTER CO., LTD. (JP) 1995-03-07 US disclosed
EP-0471498-A2 Optical resolution method KANKYO KAGAKU CENTER CO., LTD (JP) 1992-02-19 EP disclosed