SCHEMBL918459

SCHEMBL918459

C[C@@H](OC(C)(C)C)[C@H](N)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.43
NOS3 P29474 1/20 0.43
NOS2 P35228 1/20 0.43
CA12 O43570 1/20 0.32
CA14 Q9ULX7 1/20 0.32
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
DGAT1 O75907 1/20 0.30
SLC7A5 Q01650 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21841471 1.00 NOS1 (0.43) NOS1NOS3NOS2CA12CA14
SCHEMBL19981342 1.00 NOS1 (0.43) NOS1NOS3NOS2CA12CA14
SCHEMBL21841469 1.00 NOS1 (0.43) NOS1NOS3NOS2CA12CA14
SCHEMBL918458 1.00 NOS1 (0.43) NOS1NOS3NOS2CA12CA14
Hydrochloric Acid SCHEMBL2405478 0.98 NOS1 (0.42) NOS1NOS3NOS2CA12CA14
Hydrochloric Acid SCHEMBL2405476 0.98 NOS1 (0.42) NOS1NOS3NOS2CA12CA14
Acetic Acid SCHEMBL12615515 0.94 NOS1 (0.40) NOS1NOS3NOS2SLC7A5
Acetic Acid SCHEMBL29787814 0.94 NOS1 (0.40) NOS1NOS3NOS2SLC7A5
Acetic Acid SCHEMBL12615511 0.94 NOS1 (0.40) NOS1NOS3NOS2SLC7A5
SCHEMBL7367529 0.85 NOS1 (0.33) NOS1NOS3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116675736-A Synthetic method of polypeptide growth factor PSK 杭州东恒生物医药有限公司 2023-09-01 CN claimed
CN-110790674-A Method for continuously producing O-tert-butyl-L-threonine tert-butyl ester 熊飞龙 2020-02-14 CN claimed
CN-110790673-A Method for preparing O-tert-butyl-L-threonine tert-butyl ester 熊飞龙 2020-02-14 CN claimed
US-20080108787-A1 Purification of Insulin-Like Material by Reverse Phase Chromatography WOCKHARDT LIMITED (IN) 2008-05-08 US claimed
EP-1758540-A4 PURIFICATION OF INSULIN-LIKE MATERIAL BY REVERSE PHASE CHROMATOGRAPHY WOCKHARDT LTD (IN) 2007-06-20 EP claimed
EP-1758540-A1 PURIFICATION OF INSULIN-LIKE MATERIAL BY REVERSE PHASE CHROMATOGRAPHY Wockhardt Limited (IN) 2007-03-07 EP claimed
WO-2005115303-A1 PURIFICATION OF INSULIN-LIKE MATERIAL BY REVERSE PHASE CHROMATOGRAPHY WOCKHARDT LIMITED (IN) 2005-12-08 WO claimed
EP-4733307-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND USING MIXED ANHYDRIDE PROCEDURE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-04-29 EP disclosed
EP-4306530-B1 SILANE-CONTAINING CONDENSED CYCLIC DIPEPTIDE COMPOUND, PRODUCTION METHOD THEREFOR, AND METHOD FOR PRODUCING POLYPEPTIDE COMPOUND USING SAME CHUBU UNIV EDUCATIONAL FOUNDATION (JP) 2026-04-01 EP disclosed
US-20260022102-A1 1,2,4-Oxadiazole and Thiadiazole Compounds as Immunomodulators AURIGENE ONCOLOGY LIMITED (IN) 2026-01-22 US disclosed
EP-4538279-A2 REACTION AGENT FOR AMIDE REACTIONS AND AMIDE COMPOUND PRODUCTION METHOD USING SAME Chubu University Educational Foundation (JP) 2025-04-16 EP disclosed
WO-2025070753-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND USING MIXED ANHYDRIDE PROCEDURE 中外製薬株式会社 2025-04-03 WO disclosed
CN-119591674-A Cyclohexapeptide and preparation method and application thereof 陕西未来多肽生物科技有限公司 2025-03-11 CN disclosed
US-4154946-A Amino mercapto substituted acylamino acids E. R. SQUIBB & SONS, INC. (US) 1979-05-15 US disclosed
US-4146611-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1979-03-27 US disclosed
US-4129571-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-12-12 US disclosed
US-4128721-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-12-05 US disclosed
US-4127729-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-11-28 US disclosed
US-4113715-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-09-12 US disclosed
US-4091024-A Pyrrolidine and piperidine-2-carboxylic acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022102-A1 1,2,4-Oxadiazole and Thiadiazole Compounds as Immunomodulators CD274, PDCD1, PDCD1LG2 NOS1 1425/4885NOS3 1541/4885NOS2 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.