Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918774 | 0.87 | HDAC3 (0.49) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL919146 | 0.86 | HDAC3 (0.50) | ALDH1A1KMT2AMAPTLMNAHDAC3 | |
| SCHEMBL29217316 | 0.86 | KMT2A (0.51) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL920192 | 0.83 | HDAC3 (0.55) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23879940 | 0.78 | HDAC3 (0.61) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL2082472 | 0.75 | HDAC3 (0.57) | ALDH1A1KMT2AMAPTMEN1ATM | |
| SCHEMBL19501967 | 0.73 | HTT (0.72) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL10418143 | 0.71 | HDAC3 (0.62) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL10917889 | 0.71 | ALDH1A1 (0.72) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL6239079 | 0.70 | HTT (0.40) | ALDH1A1KMT2AMAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871998-B2 | Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity | ASTRAZENECA AB (SE) | 2011-01-18 | — | — | US | disclosed |