Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058575 | 0.91 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL2235188 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1TDP1TSHRENPP2 | |
| SCHEMBL232884 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL2551681 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1TDP1TSHRENPP2 | |
| SCHEMBL28645937 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL4235204 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL4235203 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1TDP1TSHRENPP2 | |
| SCHEMBL230965 | 0.77 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL4361387 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL9361017 | 0.75 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526975-B1 | Coating composition for optical plastic moldings | ITOH OPTICAL IND (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5322888-A | Curable mixture of hydrolyzable silicate, epoxy-containing silane, dicarboxylic acid or anhydride, and imidazole catalyst; protective coating for optical substrate having a high refractive index; radiation resistance | ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0526975-A2 | Coating composition for optical plastic moldings | ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |