⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060666 | 0.79 | — | — | |
| SCHEMBL6854962 | 0.68 | — | — | |
| SCHEMBL2112764 | 0.66 | — | — | |
| SCHEMBL634590 | 0.64 | — | — | |
| SCHEMBL918529 | 0.64 | — | — | |
| SCHEMBL1059440 | 0.62 | — | — | |
| SCHEMBL5223334 | 0.61 | — | — | |
| SCHEMBL7516642 | 0.60 | — | — | |
| SCHEMBL4938284 | 0.58 | — | — | |
| SCHEMBL5063666 | 0.58 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053054-B1 | METHOD FOR INTRODUCING NUCLEIC-ACID-PROTECTING GROUP | NIPPON SHINYAKU CO LTD (JP) | 2014-12-17 | — | — | EP | disclosed |
| US-8252919-B2 | 2′-hydroxy-protected ribonucleoside derivative and production method thereof | KANEKA CORPORATION (JP) | 2012-08-28 | — | — | US | disclosed |
| US-8158774-B2 | Method for introducing a nucleic-acid protecting group | NIPPON SHINYAKU CO., LTD. (JP) | 2012-04-17 | — | — | US | disclosed |
| US-8003767-B2 | Sulfonated [8,9]benzophenoxazine dyes and the use of their labelled conjugates | APPLIED BIOSYSTEMS, LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-20110098344-A1 | DRUG CARRIER | NIPPON SHINYAKU CO., LTD. (JP) | 2011-04-28 | — | — | US | disclosed |
| EP-2292270-A1 | DRUG CARRIER | Nippon Shinyaku Co., Ltd. (JP) | 2011-03-09 | — | — | EP | disclosed |
| US-20110009609-A1 | 2'-HYDROXY-PROTECTED RIBONUCLEOSIDE DERIVATIVE AND PRODUCTION METHOD THEREOF | KANEKA CORPORATION (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2258709-A1 | 2'-HYDROXYL-PROTECTED RIBONUCLEOSIDE DERIVATIVE AND MANUFACTURING METHOD OF SAME | Kaneka Corporation (JP) | 2010-12-08 | — | — | EP | disclosed |
| EP-2221347-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-2179996-A1 | Sulfonated diarylrhodamine dyes | Applera Corporation (US) | 2010-04-28 | — | — | EP | disclosed |
| EP-1278803-A2 | SULFONATED 8,9]BENZOPHENOXAZINE DYES AND THE USE OF THEIR LABELLED CONJUGATES | Applera Corporation (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6465644-B1 | CAN BE CONJUGATED TO A VARIETY OF SUBSTRATES, SUCH AS POLYNUCLEOTIDES, NUCLEOSIDES, NUCLEOTIDES, PEPTIDES, PROTEINS, ANTIBODIES, CARBOHYDRATES, LIGANDS, PARTICLES AND SURFACES. | APPLERA CORPORATION | 2002-10-15 | — | — | US | disclosed |
| US-6448407-B1 | LABELS FOR SUCH AS NUCLEOTIDES, NUCLEOSIDES, POLYPEPTIDES, POLYNUCLEOTIDES AND CARBOHYDRATES; SEQUENCING, FRAGMENT ANALYSIS, OLIGONUCLEOTIDE LIGATION, AMPLIFICATION, MINISEQUENCING, AND PRIMER EXTENSION | PE CORPORATION (NY) | 2002-09-10 | — | — | US | disclosed |
| WO-2002044416-A2 | SULFONATED DIARYLRHODAMINE DYES AS FLUORESCENT LABELS | APPLERA CORPORATION (US) | 2002-06-06 | — | — | WO | disclosed |
| WO-2002036832-A2 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHODS OF DNA SEQUENCING AND FRAGMENT ANALYSIS | APPLERA CORPORATION (US) | 2002-05-10 | — | — | WO | disclosed |
| EP-1196640-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | Applera Corporation (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001083621-A2 | SULFONATED [8,9]BENZOPHENOXAZINE DYES AND THE USE OF THEIR LABELLED CONJUGATES | APPLERA CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |
| WO-2001057264-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | APPLERA CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
| US-6221604-B1 | CONJUGATED TO SUBSTRATES SUCH AS NUCLEOSIDES OR NUCLEOTIDES AND USED AS DETECTION LABELS IN MOLECULAR BIOLOGY EXPERIMENTS; ENERGY TRANSFER DYE | PE CORPORATION | 2001-04-24 | — | — | US | disclosed |
| US-5856464-A | Selective capping solution phase oligonucleotide synthesis | LAJOLLA PHARMACEUTICAL COMPANY (US) | 1999-01-05 | — | — | US | disclosed |