⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060666 | 0.71 | — | — | |
| SCHEMBL8191873 | 0.66 | — | — | |
| SCHEMBL4938284 | 0.64 | — | — | |
| SCHEMBL634588 | 0.62 | CYP1A2 (0.30) | — | |
| SCHEMBL634589 | 0.62 | — | — | |
| SCHEMBL4601733 | 0.60 | — | — | |
| Acetonitrile SCHEMBL8910586 | 0.59 | MEN1 (0.33) | — | |
| SCHEMBL8068584 | 0.59 | TSHR (0.30) | — | |
| Acetonitrile SCHEMBL3477901 | 0.59 | MEN1 (0.33) | — | |
| SCHEMBL20438375 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419478-B1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI COR INC (US) | 2018-02-28 | — | — | EP | disclosed |
| EP-2630196-B1 | CYANINE DYES AND THEIR CONJUGATES | LI COR INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9408924-B2 | Bioconjugates of cyanine dyes | LI-COR, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150119553-A1 | BIOCONJUGATES OF CYANINE DYES | LI-COR, INC. | 2015-04-30 | — | — | US | disclosed |
| US-8927719-B2 | Cyanine dyes and their conjugates | LI-COR, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20130274452-A1 | CYANINE DYES AND THEIR CONJUGATES | MIDCAP FINANCIAL TRUST | 2013-10-17 | — | — | US | disclosed |
| EP-2630196-A1 | CYANINE DYES AND THEIR CONJUGATES | LI-COR, INC. (US) | 2013-08-28 | — | — | EP | disclosed |
| US-8481752-B2 | Fluorescent imaging with substituted cyanine dyes | LI-COR, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| WO-2012054749-A1 | CYANINE DYES AND THEIR CONJUGATES | LI-COR, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
| EP-2419478-A2 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2012-02-22 | — | — | EP | disclosed |
| US-20100323389-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| WO-2010121163-A2 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2010-10-21 | — | — | WO | disclosed |
| US-6750357-B1 | STABLE FULLY SUBSTITUTED AMIDE LINKAGE AT THE 3-POSITION CARBOXYLATE; LABELED OLIGONUCLEOTIDE CONJUGATES BY SOLID PHASE SYNTHESIS | SYNGEN, INC. | 2004-06-15 | — | — | US | disclosed |
| EP-1019887-B1 | FLUORESCENT CYANINE DYES | LI COR INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6027709-A | BENZO(E)INDOLE-BASED DYES USEFUL AS REPORTER GROUPS FOR LABELING BIOMOECULES; SOLUBILITY RETAINED BY BIOMOLECULE; ATTACHMENT TO DNA, NUCLEOTIDES, PEPTIDES, HORMONES, ENZYMES ETC.; LASER ACTIVATION | LI-COR INC. (US) | 2000-02-22 | — | — | US | disclosed |
| US-5639867-A | TTTr as protective group in nucleotide synthesis | CIBA GEIGY CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5179200-A | N4-(3-PHENYLPROPRIONYL)-2'-DEOXYCYTIDINE | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1993-01-12 | — | — | US | disclosed |