Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186042 | 1.00 | LSS (0.43) | LSSHPGDKIF11ALDH1A1LMNA | |
| SCHEMBL9190344 | 0.96 | LSS (0.41) | LSSHPGDKIF11ALDH1A1LMNA | |
| SCHEMBL9190337 | 0.96 | LSS (0.41) | LSSHPGDKIF11ALDH1A1LMNA | |
| SCHEMBL9190352 | 0.96 | LSS (0.41) | LSSHPGDKIF11ALDH1A1LMNA | |
| SCHEMBL9187378 | 0.92 | LSS (0.43) | LSSHPGDKIF11ALDH1A1LMNA | |
| SCHEMBL9187370 | 0.92 | LSS (0.43) | LSSHPGDKIF11ALDH1A1LMNA | |
| SCHEMBL9188927 | 0.90 | LSS (0.47) | LSSHPGDKIF11ALDH1A1LMNA | |
| SCHEMBL9188919 | 0.90 | LSS (0.47) | LSSHPGDKIF11ALDH1A1LMNA | |
| SCHEMBL9189161 | 0.88 | LSS (0.41) | LSSHPGDKIF11ALDH1A1LMNA | |
| SCHEMBL9190086 | 0.88 | LSS (0.48) | LSSHPGDKIF11KMT2ASLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423520-B1 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GMBH (DE) | 1995-08-02 | — | — | EP | disclosed |
| EP-0423520-A2 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GmbH (DE) | 1991-04-24 | — | — | EP | disclosed |